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In This Issue:
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Product Spotlight and Applications
Autophagy Antibodies Designed with Epishot™ Technology
MAPLC3 – A Hallmark Autophagy Protein
New Products
Apoptosis/DNA Repair
Autophagy
Cell Cycle Regulation
Cell Signaling
Histone Demethylation
Protein Phosphorylation
Transcription Regulation
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Product Spotlight and Applications
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Autophagy Abs Designed with Epishot™ Technology
Autophagy plays a role in development, aging, immunity and cell death and is associated with human cancers and a number of neurodegenerative diseases such as Parkinson’s, Huntington’s and Alzheimer’s diseases.
We have expanded our selection of autophagy products and announce a comprehensive pathway-based collection of over
60 antibodies targeting autophagic proteins.
Our
Epishot™ Antigen Prediction Screen
maximizes the epitope specificity of these autophagy antibodies. This newly expanded autophagy antibody product line includes these protein targets: APG8 (MAPLC3) and APG8b, APG3L, APG4, APG5, APG7, APG9, APG12, APG16, Beclin, and Rab24.
See Product Listing
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LC3 Protein
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MAPLC3: A Hallmark Autophagy Protein
Our anti-APG8 antibodies are specific for the hallmark autophagy protein MAPLC3, which associate with autophagosomal vacuoles (autophagosomes) formed upon induction of autophagy. These APG8a (MAPLC3) antibodies have proven to be a successful detection tool in a neuronal mouse model system
Read Full Article
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LC3 in MouseNeuronal Model
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New Products
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Apoptosis/DNA Repair
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Catalog #
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Product Name
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AP1922d
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RUVBL2 Antibody (C-term)
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AP7194a
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RIPK5 Antibody (N-term)
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AP7194c
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RIPK5 Antibody (Center)
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Cell Cycle Regulation
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Catalog #
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Product Name
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AP3206a
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Phospho-P53-S9 Antibody
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AP7196b
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PKMYT1 Antibody (C-term)
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AP7200b
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RIOK1 Antibody (C-term)
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Cell Signaling
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Catalog #
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Product Name
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AM3111a
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Gab1 antibody
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AP7197b
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PRKY Antibody (C-term)
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Histone Demethylation
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Catalog #
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Product Name
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AP1022b
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JMJD3 Antibody (C-term)
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Protein Phosphorylation
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Catalog #
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Product Name
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AP7096b
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ROCK1 Antibody (C-term)
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AP7197b
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PRKY Antibody (C-term)
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AP7200b
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RIOK1 Antibody (C-term)
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AP7202b
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KSR1 Antibody (C-term)
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AP7202a
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KSR1 Antibody (N-term E173)
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Transcription Regulation
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Catalog #
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Product Name
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AP1022b
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JMJD3 Antibody (C-term)
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More New Products
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Catalog #
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Product Name
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AP1968a
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Importin alpha-4 Antibody (N-term)
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AP7198a
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PTK9 Antibody (N-term)
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RP1008a
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Human Basic Fibroblast Growth Factor (bFGF)
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View our expanded product offering for protein modification research:
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Tech Corner
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Q:
My protein migrated at a higher molecular weight than expected using SDS page. How can I check to see if it is sumoylated?
A:
Sumoylation is a novel post-translational modification system that has been the object of intense interest in recent years. Analogous to ubiquitin, reversible covalent attachment of SUMO (
s
mall
u
biquitin-like
mo
difier) to lysine residues in substrate proteins alters the properties of the proteins to which SUMO conjugates. However, in contrast to ubiquitin, SUMO conjugation does not typically lead to degradation of the substrate; rather, sumoylation orchestrates a diverse array of effects on many different biological processes, including protein localization and stability, transcriptional activities, nucleocytoplasmic signaling and transport, and genomic replication, as well as the regulation of gene expression and viral reproduction.
You can use our
SUMOplot™
bioinformatics tool in order to investigate if your protein is sumoylated.
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Company Info
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Abgent OLAW Assurance
Abgent is committed to quality assurance and is approved by the Office of Laboratory Animal Welfare, Division of Assurances in the USA. Our OLAW Assurance No. is A4534-01.
Abgent Distributors:
Based in Switzerland Abgent Europe
serves our European customers and our distribution network. Customer and technical service staff provide local language support in five languages. Over 90% of Abgent products are available for next day shipping to any European country. Visit Abgent Europe at these
upcoming meetings.
View All Abgent Distributors
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Abgent, Inc. (USA)
6310 Nancy Ridge Dr.
San Diego, CA 92121
1.888.735.7227
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