|
|
|
|
Cell Function and Disease
|
|
|
Antibodies against p53, ABL1, IKK, and More
|
|
Browse our monoclonal and polyclonal antibodies against proteins
associated with diseases like cancer, Alzheimer's, inflammation, and
more.
|
|
Legend
>
|
|
|
|
Posttranslational modifications functionally imprint protein
phenotype via changes in protein structure and function and are
thereby a key for properly tasking proteins within the cell. In
addition, specific protein-protein interactions can control the
expression of intracellular phenotype. The proper modification of
proteins either through covalent modification or protein-protein
interactions is a key aspect determining cellular health and disease.
Comparing protein profiles from normal cells with those in clinical
pathology is expected to reveal new insights into the molecular
mechanisms associated with diverse disease-related processes such a
carcinogenesis, apoptosis, autoimmunity, viral infections, and
neurological and degenerative disorders.
|
Legend
|
Qualification:
DB
(Dot Blot)
IF
(Immunofluorescence)
IHC
(Immunohistochemistry)
IP
(Immunoprecipitation)
W
(Western Blot)
|
Specificity
:
B
(Bovine),
C
(Chicken),
D
(Drosphilia),
E
(C. Elegans),
EBV
(EBV),
G
(Neisseria Gonorrhoeae),
H
(Human),
Ha
(Hamster),
M
(Mouse),
P
(Pig),
Pr
(Monkey)
, R
(Rat),
Rb
(Rabbit),
S
(SARS),
V
(Vaccinia Virus),
X
(Xenopus),
Y
(Yeast),
Z
(Zebrafish)
*Additional species predicted to react based on 93-100% sequence homology.
|
|
|
Autophagy - Featured Antibodies
|
|
|
Catalog #
|
Target
|
Qualification
|
Specificity
|
|
AP8104c
NEW
|
APG1 (ULK1) (Center)
|
W
|
H, M
|
|
AP8104d
NEW
|
APG1 (ULK1) (Center)
|
W
|
H
|
|
AP8104b
|
APG1 (ULK1) (C-term )
|
W
|
H
|
|
AP8104a
NEW
|
APG1 (ULK1) (N-term)
|
W
|
H
|
|
AP1815a
|
APG10L (N-term)
|
IHC
|
H
|
|
AP1151a
|
APG12L (N-term)
|
IF
|
H
|
|
AP1816a
|
APG12L (N-term)
|
IHC, W
|
H
|
|
AP1816b
|
APG12L (P42)
|
IHC
|
H
|
|
AP1816c
|
APG12L (P46)
|
IHC
|
H
|
|
AP1817a
|
APG16L (N-term)
|
IHC
|
H
|
|
AP1817b
|
APG16L (L176)
|
IHC, W
|
H, M
|
|
AP1817c
|
APG16L (C-term)
|
IHC, W
|
H
|
|
AP1807a
|
APG3L (N-term)
|
W
|
H, B*, M*, R*
|
|
AP1807b
|
APG3L (C-term)
|
W
|
H, B*, M*, R*
|
|
AP1807c
|
APG3L (C-term K183)
|
W
|
H, M, B*, R*
|
|
AP1808a
|
APG4A (N-term)
|
IHC, W
|
H, M
|
|
AP1808b
|
APG4A (Center)
|
IHC, W
|
H, B*
|
|
AP1808c
|
APG4A (C-term)
|
IHC, W
|
H, M, B*, R*
|
|
AP1809a
|
APG4B (N-term)
|
IHC, W
|
H, M
|
|
AP1809b
|
APG4B (G93)
|
IHC, W
|
H, M, B*
|
|
AP1809c
|
APG4B (C-term)
|
IHC, W
|
H
|
|
AP1809d
NEW
|
APG4B (E273)
|
IHC, W
|
H
|
|
AP1810a
|
APG4C (N-term)
|
IHC, W
|
H, M
|
|
AP1810b
|
APG4C (Center)
|
IHC, W
|
H
|
|
AP1810c
|
APG4C (C-term)
|
IHC, W
|
H, M
|
|
AP1811a
|
APG4D (N-term)
|
IHC, W
|
H, M
|
|
AP1811b
|
APG4D (Center)
|
IHC, W
|
H, M, CM*
|
|
AP1811c
|
APG4D (C-term)
|
IHC, W
|
H, CM*, P*
|
|
AP1812a
|
APG5L (N-term)
|
IHC, W
|
H, M, B* C*, R*, P*, Z*
|
|
AP1812b
|
APG5L (C-term)
|
IHC, W
|
H, M, C*, R*
|
|
AP1813a
|
APG7L (N-term)
|
IHC, W
|
H, M, R*
|
|
AP1813b
|
APG7L (Center)
|
IHC, W
|
H, M, C*, R*
|
|
AP1813c
|
APG7L (R509)
|
IHC, W
|
H, M, R*
|
|
AP1813d
|
APG7L (C-term)
|
IHC, W
|
H, C*, M*, R*
|
|
AM1800a
|
APG8 (MAP1LC3)
|
W
|
H, M, R
|
|
AP1801a
|
APG8a (MAP1LC3A) (N-term)
|
IHC, W
|
H, M, R, B*, C*, Z*
|
|
AP1801b
NEW
|
APG8a (MAP1LC3A) (P45)
|
IHC, W
|
H
|
|
AP1801c
NEW
|
APG8a (MAP1LC3A) (I31)
|
IHC, W
|
H
|
|
AP1801d
NEW
|
APG8a (MAP1LC3A) (D106)
|
W
|
H
|
|
AP1805a
|
APG8a Cleaved (MAP1LC3A)
|
IHC, W
|
H, M, B*, C*, CM*, R*, Z*
|
|
AP1803a
|
APG8a/b (MAP1LC3A/B)
|
IHC
|
H, M, R, C*, Z*
|
|
AP1802a
|
APG8b (MAP1LC3B) (N-term)
|
IF, IHC, W
|
H, M, R, B*, C*, Z*
|
|
AP1802b
|
APG8b (MAP1LC3B) (C-term)
|
IHC, W
|
H, M, B*, C*, CM*
|
|
AP1806a
|
APG8b Cleaved (MAP1LC3B)
|
IF, IHC, W
|
H, M, B*, C*, R*
|
|
AP1804a
|
APG8c (MAP1LC3C) (N-term)
|
IHC, W
|
H, M, R
|
|
AP1804b
|
APG8c (MAP1LC3C) (C-term)
|
IHC
|
H
|
|
AP1814a
|
APG9L1 (N-term)
|
IHC, W
|
H
|
|
AP1814b
|
APG9L1 (Center)
|
IHC, W
|
H
|
|
AP1814c
|
APG9L1 (C-term)
|
IHC, W
|
H
|
|
AM1818a
NEW
|
Beclin 1 (BECN1, APG6) Monoclonal
|
W
|
H
|
|
AP1818a
|
BECN1 (APG6) (Q196)
|
IHC, W
|
H, M
|
|
AP1818b
|
BECN1 (APG6) (E225)
|
IHC, W
|
H, M
|
|
AP1818c
|
BECN1 (APG6) (C-term)
|
IHC, W
|
H, M
|
|
AP1821a
NEW
|
GABARAP (N-term)
|
IHC, W
|
H
|
|
AP1851a
NEW
|
Kinase PI3KC3 (N-term G24)
|
IHC, W
|
H
|
|
AP1851b
NEW
|
Kinase PI3KC3 (C-term E785)
|
IHC, W
|
H
|
|
AP1851c
NEW
|
Kinase PI3KC3 (Center K269 )
|
IHC, W
|
H
|
|
AP1851d
NEW
|
Kinase PI3KC3 (Center E501)
|
IHC, W
|
H
|
|
AP8014a
|
Kinase PI3KC3 (N-term )
|
IHC, W
|
H
|
|
AP8014b
|
Kinase PI3KC3 (C-term )
|
IHC
|
H
|
|
AP1823a
NEW
|
LAMP1 (N-term)
|
W
|
H
|
|
AP1823b
NEW
|
LAMP1 (C-term)
|
W
|
H
|
|
AP1824b
NEW
|
LAMP2 (C-term)
|
W
|
H
|
|
AP1824c
NEW
|
LAMP2 (Center)
|
W
|
H
|
|
AP1819a
|
RAB24 (N-term)
|
IHC, W
|
H, M
|
|
AP1819b
|
RAB24 (Center)
|
IHC, W
|
H, M
|
|
AP1819c
|
RAB24 (C-term)
|
IHC, W
|
H, M
|
|
AP1820a
|
RGS19 (N-term)
|
IHC, W
|
H
|
|
AP1820b
|
RGS19 (Center)
|
IF, IHC, W
|
H, M
|
|
AP1820c
|
RGS19 (C-term)
|
IHC
|
H
|
|
AP2183b
|
SQSTM1 (p62) (C-term )
|
IHC, W
|
H
|
|
AP1850b
NEW
|
UVRAG (C-term)
|
IF, IP
|
H, M
|
|
AP1850c
NEW
|
UVRAG (Center)
|
IHC, W
|
H, M
|
|
AP1850d
NEW
|
UVRAG (L133)
|
IF, IHC, W
|
H, M
|
|
AP1850e
NEW
|
UVRAG(C-term L555)
|
W
|
H
|
|
AS1001a
|
Autophagy Pathway Sampler Kit
|
|
|
|
SP1040a
NEW
|
Autophagy Inducer: Beclin1 BH3 domain (Cell Permeable, Human, WT)
|
|
|
|
SP1041a
NEW
|
Autophagy Inducer: Beclin1 BH3 domain (Human, WT)
|
|
|
|
SP1043a
NEW
|
Autophagy Inducer: Beclin1 BH3 domain (Cell Permeable, Zebrafish, WT)
|
|
|
|
SP1044a
NEW
|
Autophagy Inducer: Beclin1 BH3 domain (Zebrafish, WT)
|
|
|
|
SP1046a
NEW
|
Autophagy Inducer Control: Beclin1 BH3 domain mutant (Cell Permeable, Human, MT1-L116A)
|
|
|
|
SP1046b
NEW
|
Autophagy Inducer Control: Beclin1 BH3 domain mutant (Cell Permeable, Human, MT2-F123A)
|
|
|
|
SP1047a
NEW
|
Autophagy Inducer Control: Beclin1 BH3 domain mutant (Human, MT1-L116A)
|
|
|
|
SP1047b
NEW
|
Autophagy Inducer Control: Beclin1 BH3 domain mutant (Human, MT2-F123A)
|
|
|
|
|
|
|