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Abgent Pathway Resource

Sep 14, 2017

The Abgent Biological Pathway Collection

The Abgent biological pathway collection presents critical protein networks involved in cellular health and disease. Concise descriptions of essential pathways accompany interactive maps illustrating key interactions driving signaling and function. To select the right tool for your research, click on protein icons in the maps to view target-specific antibody products, produced by Abgent.

Abgent is an original manufacturer of antibodies focused on targets covering the major research areas impacting health and disease, including cancer, metabolism, neuroscience, cardiovascular, immunology, and stem cells.

HER_ErbB Pathway

Her/ErbB receptor tyrosine kinases are activated upon ligand binding and dimerization. They signal through Akt, MAPK, and other pathways to regulate proliferation, differentiation, apoptosis, migration, and motility ...

Apoptosis Pathway

The mammalian target of rapamycin (mTOR) signaling pathway integrates intracellular and extracellular signals to regulate cell metabolism, growth, proliferation and survival...

Cell Cycle Control: G1/S Checkpoint Pathway

Cell cycle arrest provides time crucial for repair of DNA damage, preserving genomic integrity. Growth arrest activates through checkpoint pathways that delay cell cycle progression ...

mTOR Signaling Pathway

The mammalian target of rapamycin (mTOR) signaling pathway integrates intracellular and extracellular signals to regulate cell metabolism, growth, proliferation and survival...

Angiogenesis Pathway

Angiogenesis is the process of creating new blood vessels from preexisting blood vessels. This process is essential for healing, growth, development...

Notch Signaling Pathway

The Notch signaling pathway is an evolutionarily conserved pathway operating in multicellular organisms. This pathway plays a significant role in cell differentiation during embryonic development and maintenance of adult tissue homeostasis...

Jak/Stat Signaling Pathway

The Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathway cascades to transduce cellular signals for development and homeostasis...

NFKappa Pathway

Nuclear factor-kB (NF-kB)/Rel proteins control genes involved in inflammation, innate and adaptive immunity, B-cell development inflammation, and stress responses...

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