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Catalog #
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Source:
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Lot #
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Size:
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AP1471b
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Rabbit
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SA071205AK
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0.1 mg
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Concentration:
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Accession:
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Clone Name:
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Isotype:
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0.25 mg/ml
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NP_387450, Q9ULB5
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RB12865
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Rabbit Ig
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Applications:
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Reactivity:
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MW (kDa):
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WB, E
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H
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87105 Da
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Target/Specificity:
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This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human CDH7.
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Other Names:
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CDH7L1
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Application Data:
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Western blot analysis of CDH7 Antibody (C-term) (Cat.#AP1471b) in K562 cell line lysates (35ug/lane). CDH7 (arrow) was detected using the purified Pab (1:60 dilution). |
Formalin-fixed and paraffin-embedded human prostata carcinoma reacted with CDH7 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
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Background:
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CDH7 is a type II classical cadherin from the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures.
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Background References:
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- Moore,R., Oncogene 23 (40), 6726-6735 (2004)
- Kools,P., Genomics 68 (3), 283-295 (2000)
- Shimoyama,Y., Biochem. J. 349 (PT 1), 159-167 (2000)
- Kremmidiotis,G., Genomics 49 (3), 467-471 (1998)
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Product Citations:
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Application Notes:
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| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blotting | 1:50~100 |
| Immunohistochemistry | 1:10~50 |
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Format:
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Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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Storage:
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Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
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Precautions:
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This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
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