|
Catalog #
|
Source:
|
Lot #
|
Size:
|
|
AP6274a
|
Rabbit
|
SH070906F
|
0.1 mg
|
|
Concentration:
|
Accession:
|
Clone Name:
|
Isotype:
|
|
0.25 mg/ml
|
NP_057356, Q14106
|
RB12392
|
Rabbit Ig
|
|
Applications:
|
Reactivity:
|
MW (kDa):
|
|
WB, IHC, E
|
H
|
36501 Da
|
|
Target/Specificity:
|
|
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human TOB2.
|
|
Other Names:
|
|
KIAA1663; TOB4; TROB2
|
|
Application Data:
|
Western blot analysis of TOB2 Antibody (N-term) (Cat. #AP6274a) in HepG2 cell line lysates (35ug/lane). TOB2 (arrow) was detected using the purified Pab. |
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with TOB2 antibody (N-term)(Cat.#AP6274a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
|
|
Background:
|
|
TOB2 belongs to the TOB /BTG1 family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.
|
|
Background References:
|
- Sasajima,H., Eur. J. Biochem. 269 (14), 3596-3604 (2002)
- Yoshida,Y., Jpn. J. Cancer Res. 92 (6), 592-596 (2001)
- Suzuki,T., Genes Cells 6 (2), 131-138 (2001)
- Ikematsu,N., Oncogene 18 (52), 7432-7441 (1999)
|
|
Product Citations:
|
|
|
|
Application Notes:
|
| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Western blot | 1:50~100 |
| Immunohistochemistry | 1:50 |
|
|
Format:
|
|
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
|
|
Storage:
|
|
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
|
|
Precautions:
|
|
This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
|