|
Catalog #
|
Source:
|
Lot #
|
Size:
|
|
AP7031a
|
Rabbit
|
SH070919H
|
0.1 mg
|
|
Concentration:
|
Accession:
|
Clone Name:
|
Isotype:
|
|
0.25 mg/ml
|
NP_775739, Q7L9L4
|
RB12525
|
Rabbit Ig
|
|
Applications:
|
Reactivity:
|
MW (kDa):
|
|
IHC, E
|
H
|
24960 Da
|
|
Target/Specificity:
|
|
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human MOB4A.
|
|
Other Names:
|
|
MOBKL1A; MATS2; Mob1B; MGC33910
|
|
Application Data:
|
Formalin-fixed and paraffin-embedded human brain tissue reacted with MOB4A antibody (N-term)(Cat.#AP7031a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
|
|
Background:
|
|
MOB4A is similar to the yeast Mob1 protein. Yeast Mob1 binds Mps1p, a protein kinase essential for spindle pole body duplication and mitotic checkpoint regulation. Mob4A regulates NDR1 and NDR2 kinase activity, widely expressed nuclear serine-threonine kinases that have been implicated in cell proliferation and/or tumor progression.
|
|
Background References:
|
- Bichsel,S.J.,J. Biol. Chem. 279 (34), 35228-35235 (2004)
- Devroe,E.,J. Biol. Chem. 279 (23), 24444-24451 (2004)
|
|
Product Citations:
|
|
|
|
Application Notes:
|
| The suggested dilution is: | |
| ELISA | 1:1,000 |
| Immunohistochemistry | 1:50 |
|
|
Format:
|
|
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
|
|
Storage:
|
|
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
|
|
Precautions:
|
|
This product is for research use only. Not for use in diagnostic
or therapeutic procedures.
|
