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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Anti-Noxa Antibody    

Anti-Noxa Antibody

Rabbit Anti-Mouse Polyclonal Antibody

  • IHC - Anti-Noxa Antibody  ABD10011
    Formalin fixed, paraffin embedded human stomach stained with Rabbit anti Human NOXA following heat mediated antigen retrieval using sodium citrate buffer (pH6.0)
  • WB - Anti-Noxa Antibody  ABD10011
    Western blot analysis of human stomach tissue lysate probed with Rabbit anti NOXA at 0.5(A), 1(B) and 2(C) ug/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9JM54
Reactivity Mouse
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 11566 Da
Additional Information
Other Species H,Rat
Purification Antisera to NOXA were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen Synthetic peptide corresponding to N-terminus of mouse NOXA.
Shelf Life 18 months from the date of despatch.
Gene ID 58801
Other Names Phorbol-12-myristate-13-acetate-induced protein 1, Protein Noxa, Pmaip1, Noxa
Target/Specificity Rabbit anti-Murine Noxa antibody recognises murine Noxa, an ~11kDa member of the BH3-only proapoptotic protein family. Noxa is localized to the mitochondria and is a transcriptional target of p73, p53 and BH3-only proteins. It is thought to induce apoptosis when activated, lowering the activity of anti-apoptotic Bcl-2-like proteins. It can be upregulated by mitogenic activation, independently of p53. In humans, along with Mcl-1 it is thought to form a selective pathway that restrains lymphocyte proliferation.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Noxa Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Oda, E. et al. (2000) Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis.
Science 288:1053–1058.2. Alves, N. et al. (2006) The Noxa/Mcl-1 axis regulates susceptibility to apoptosis under glucose limitation in dividing T cells.
Immunity. 24:703-716.

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Cat# ABD10011
(40 western blots)
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