|Application ||WB, IHC-F|
|Calculated MW||115860 Da|
|Purification||Antisera to human CD289 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||A synthetic peptide corresponding to a 15 amino acid sequence located near the centre of human CD289.|
|Shelf Life||18 months from the date of despatch.|
|Other Names||Toll-like receptor 9, CD289, TLR9|
|Target/Specificity||Rabbit anti-Human CD289 antibody recognizes human CD289, otherwise known as toll receptor 9, a member of the evolutionarily conserved toll-like receptor family (TLRs), which play an important role in the recognition of invading microbial pathogens during innate immunity.CD289 is expressed preferentially by the spleen, lymph node, bone marrow and peripheral blood leucocytes and recognizes viral DNA and unmethylated CpG sequences in bacterial DNA. Unlike other TLRs, TLR9 is dependant upon the adaptor molecule MyD88 for signaling activation.Rabbit anti-Human CD289 antibody has been shown as suitable for use in IHC on human Jurkat cell cytospins @ 2ug/ml.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD289 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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