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Anti-SUMO-1 (N-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • ICC - Anti-SUMO-1 (N-Terminal) Antibody  ABD10017
    Immunocytochemical staining of HL-60 cells with Rabbit anti Human SUMO-1
  • WB - Anti-SUMO-1 (N-Terminal) Antibody  ABD10017
    Western blot analysis of whole cell lysate from HL-60 human promyelocytic leukemia cells probed with Rabbit anti Human SUMO-1
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P63165
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 11557 Da
Additional Information
Other Species Rat,M
Purification Antisera to human SUMO-1 were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG prepared by affinity chromatography.
Immunogen 14 amino acid peptide sequence near the amino terminus of human SUMO-1.
Shelf Life 18 months from the date of despatch.
Gene ID 7341
Other Names Small ubiquitin-related modifier 1, SUMO-1, GAP-modifying protein 1, GMP1, SMT3 homolog 3, Sentrin, Ubiquitin-homology domain protein PIC1, Ubiquitin-like protein SMT3C, Smt3C, Ubiquitin-like protein UBL1, SUMO1, SMT3C, SMT3H3, UBL1
Target/Specificity ABD10017 detects an epitope within the N-terminal (NT) region of small ubiquitin-related modifier-1 (SUMO-1). SUMO-1 is an 11kD protein which structurally related to ubiquitin, and is added to proteins as a form of post-translational modification known as sumoylation. Sumoylation can be cell cycle regulated, stimulated upon stress or induced by DNA damage, and binding elicits individual effects for each protein. Effects include changes to protein stability, nuclear-cytosolic transport, and transcriptional regulation (mostly transcriptional repression). Alternate transcriptional splice variants encoding different isoforms have been characterized.
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-SUMO-1 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Melchior, F. and Hengst, L. (2002) SUMO-1 and p53.
Cell Cycle. 1: 245-249.2. Verger, A et al. (2003) Modification with SUMO. A role in transcriptional regulation.
EMBO Rep. 4: 137-142.

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Cat# ABD10017
(40 western blots)
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