|Calculated MW||23551 Da|
|Purification||Purified IgG was prepared by affinity chromatography.|
|Immunogen||A 15 amino acid peptide located near the carboxy terminus of human SOCS1.|
|Shelf Life||18 months from the date of despatch.|
|Other Names||Suppressor of cytokine signaling 1, SOCS-1, JAK-binding protein, JAB, STAT-induced STAT inhibitor 1, SSI-1, Tec-interacting protein 3, TIP-3, SOCS1, SSI1, TIP3|
|Target/Specificity||ABD10020 recognises Suppressor of cytokine signalling 1 (SOCS1), a 24kDa member of the Suppressor of cytokine signalling family. SOCS1 acts downstream of cytokine receptors and plays a role in the negative regulation of cytokine signalling. It acts mainly on the Janus kinase (JAK)/signal transducers and activators of transcription-3 (STAT3) pathway but also inhibits signalling by cytokines such as insulin and toll-like receptors. Furthermore SOCS1 is involved in ubiquitin-dependent protein degradation, plays a role in T cell activation and in the regulation of IL-6, IL-4, IL-12 and IL-15. SOCS1 is expressed ubiquitously and at elevated levels in the spleen, small intestine and peripheral blood leukocytes.|
|Preservative & Stabilisers||0.02% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-SOCS-1 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.