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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-NAK (C-Terminal) Antibody    

Anti-NAK (C-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-NAK (C-Terminal) Antibody  ABD10022
    Immunohistochemical staining of MOLT4 cells with Rabbit anti Human NAK
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UHD2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 83642 Da
Additional Information
Other Species M,Rat
Purification Antiserum to human NAK was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen A peptide corresponding to 17 amino acids near the carboxy terminus of human NAK.
Shelf Life 18 months from the date of despatch.
Gene ID 29110
Other Names Serine/threonine-protein kinase TBK1,, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1, TBK1, NAK
Target/Specificity Rabbit anti-NAK (C-Terminal) antibody recognizes human NF-kB-activating kinase (NAK), otherwise known as TANK-binding kinase 1 (TBK1). It is involved in the signalling cascade of NF-kB activation by directly phosphorylating and activating IKK Beta. It also mediates the production of IFN Beta and CCL5 and plays a key role in the innate immune response. In addition, it phosphorylates and activates the interferon regulatory factors -3 and -7, eventually leading to the development of a cellular antiviral state. It may also be involved in the induction of the antiviral interferon response. NAK is expressed ubiquitously, with higher expression in testis.Rabbit anti-NAK (C-Terminal) antibody does not cross-react with IKK Alpha, IKK Beta, IKK Gamma or IKK Epsilon.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-NAK (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD10022
(40 western blots)
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