|Application ||WB, IHC-F|
|Calculated MW||83642 Da|
|Purification||Antiserum to human NAK was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||A peptide corresponding to 17 amino acids near the carboxy terminus of human NAK.|
|Shelf Life||18 months from the date of despatch.|
|Other Names||Serine/threonine-protein kinase TBK1, 184.108.40.206, NF-kappa-B-activating kinase, T2K, TANK-binding kinase 1, TBK1, NAK|
|Target/Specificity||Rabbit anti-NAK (C-Terminal) antibody recognizes human NF-kB-activating kinase (NAK), otherwise known as TANK-binding kinase 1 (TBK1). It is involved in the signalling cascade of NF-kB activation by directly phosphorylating and activating IKK Beta. It also mediates the production of IFN Beta and CCL5 and plays a key role in the innate immune response. In addition, it phosphorylates and activates the interferon regulatory factors -3 and -7, eventually leading to the development of a cellular antiviral state. It may also be involved in the induction of the antiviral interferon response. NAK is expressed ubiquitously, with higher expression in testis.Rabbit anti-NAK (C-Terminal) antibody does not cross-react with IKK Alpha, IKK Beta, IKK Gamma or IKK Epsilon.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-NAK (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.