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Anti-Human Bcl-xL Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-Human Bcl-xL Antibody  ABD10031
    Western Blot analysis of whole cell lysate from A459 human lung adenocarcinoma cells probed with Rabbit anti Human Bcl-xL at 1(A) and 2(B) ug/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q07817
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 26049 Da
Additional Information
Purification Antiserum to Bcl-xL was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by immunoaffinity chromatography.
Immunogen A peptide corresponding to 14 amino acids near the carboxy terminus of human Bcl-xL precursor.
Shelf Life 18 months from the date of despatch.
Gene ID 598
Other Names Bcl-2-like protein 1, Bcl2-L-1, Apoptosis regulator Bcl-X, BCL2L1, BCL2L, BCLX
Target/Specificity Rabbit anti-Human Bcl-xL antibody recognizes the long isoform of human Bcl-2-like protein 1, otherwise known as Bcl-xL, located on the mitochondrial membrane. The Bcl-xL isoform (the longer isoform) is a potent inhibitor of apoptosis. It appears to regulate cell death by binding to and blocking the voltage-dependent anion channel, thereby preventing the release of the caspase activator cytochrome c. High expression of Bcl-xL in tumours correlates to advanced disease and a poor prognosis.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Bcl-xL Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD10031
(40 western blots)
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