|Calculated MW||76613 Da|
|Purification||Antisera to human LGP2 (N-Terminal) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.|
|Immunogen||Peptide corresponding to a 14 amino acid sequence from near the amino terminus of human LGP2.|
|Shelf Life||18 months from the date of despatch.|
|Other Names||Probable ATP-dependent RNA helicase DHX58, 188.8.131.52, Probable ATP-dependent helicase LGP2, Protein D11Lgp2 homolog, RIG-I-like receptor 3, RLR-3, RIG-I-like receptor LGP2, RLR, DHX58, D11LGP2E, LGP2|
|Target/Specificity||Rabbit anti-LGP2 (N-Terminal) antibody recognizes human Probable ATP-dependent helicase LGP2 (LGP2), also known as DHX58, a 768aa cytoplasmic protein belonging to the Helicase family.LGP2 is a negative regulator of host innate immune defense against viruses. The repressor domain of LGP2 interacts with RIG-I and negatively regulates RIG-I mediated signaling. LGP2 binds to dsRNA produced during viral replication, in particuliar HCV RNA.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-LGP2 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Akira S, et al (2006) Pathogen recognition and innate immunityCell; 124:783-8012. Iwasaki A et al (2004) Toll-like receptor control of the adaptive immune responses. Nat. Immunol. 5:987-95.3. Yoneyama M, et al (2004) The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5:730-7. Nat. Immunol. 5:730-737
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.