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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-LGP2 (N-Terminal) Antibody    

Anti-LGP2 (N-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-LGP2 (N-Terminal) Antibody  ABD10033
    Western blot analysis of whole cell lysate from MDA-MB-361 human breast adenocarcinoma cells probed with Rabbit anti Human LGP2 at 0.5(A) and 1(B) ug/ml
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96C10
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 76613 Da
Additional Information
Other Species M,Rat
Purification Antisera to human LGP2 (N-Terminal) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared from whole serum by affinity chromatography.
Immunogen Peptide corresponding to a 14 amino acid sequence from near the amino terminus of human LGP2.
Shelf Life 18 months from the date of despatch.
Gene ID 79132
Other Names Probable ATP-dependent RNA helicase DHX58,, Probable ATP-dependent helicase LGP2, Protein D11Lgp2 homolog, RIG-I-like receptor 3, RLR-3, RIG-I-like receptor LGP2, RLR, DHX58, D11LGP2E, LGP2
Target/Specificity Rabbit anti-LGP2 (N-Terminal) antibody recognizes human Probable ATP-dependent helicase LGP2 (LGP2), also known as DHX58, a 768aa cytoplasmic protein belonging to the Helicase family.LGP2 is a negative regulator of host innate immune defense against viruses. The repressor domain of LGP2 interacts with RIG-I and negatively regulates RIG-I mediated signaling. LGP2 binds to dsRNA produced during viral replication, in particuliar HCV RNA.
Preservative & Stabilisers 0.02% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-LGP2 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Akira S, et al (2006) Pathogen recognition and innate immunity
Cell; 124:783-8012. Iwasaki A et al (2004) Toll-like receptor control of the adaptive immune responses.
Nat. Immunol. 5:987-95.3. Yoneyama M, et al (2004) The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5:730-7.
Nat. Immunol. 5:730-737

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Cat# ABD10033
(40 western blots)
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