|Application ||WB, IHC-P|
|Calculated MW||49799 Da|
|Purification||Antiserum to human ECSIT (CT) was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by ion exchange chromatography.|
|Immunogen||A peptide corresponding to 14 amino acids near the carboxy terminus of human ECSIT.|
|Shelf Life||18 months from the date of despatch.|
|Other Names||Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, Protein SITPEC, Ecsit, Sitpec|
|Target/Specificity||Rabbit anti-ECSIT (C-Terminal) antibody recognizes Ecsit (Evolutionary conserved signalling intermediate in Toll pathway), an adaptor protein of the Toll-like and IL-1 receptor signalling pathway. It is involved in the activation of NF-kappa-B, acting as a regulator of MEKK-1 processing by promoting its proteolytic activation. Ecsit is also involved in the bone morphogenetic protein signalling pathway and is required for normal embryonic development.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-ECSIT (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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