|Application ||WB, IHC-P, IF|
|Other Accession||Q6AYC2, A1A4Y4|
|Calculated MW||46552 Da|
|Purification||Antiserum to human IRGM was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to a 14 aa sequence from near the centre of human IRGM.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Immunity-related GTPase family M protein 1, 3.6.5.-, Interferon-inducible GTPase 3, Interferon-inducible protein 1, LPS-stimulated RAW 264.7 macrophage protein 47, LRG-47, Irgm1, Ifi1, Iigp3, Irgm|
|Target/Specificity||Rabbit anti-IRGM (Internal Region) antibody recognizes human Immunity-related GTPase family M protein (IRGM), also known as LRG47.IRGM is a putative GTPase required for clearance of bacterial and protozoan infections. It funtions in the innate immune response, most likely through regulation of autophagy.IRGM may also function in the regulation of proinflammatory cytokine production and in macrophage adhesion and motility.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-IRGM (Internal Region) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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