|Application ||WB, IHC-P|
|Other Accession||Q9CQY1, Q2TBJ5|
|Calculated MW||15113 Da|
|Purification||Antiserum to human ATG12 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to a 15 aa sequence from near the centre of human ATG12.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like, ATG12, APG12, APG12L|
|Target/Specificity||Rabbit anti-ATG12 (Internal Region) antibody recognizes human Autophagy-related protein 12 (ATG12). ATG12, a member of the autophagy protein family, forms a conjugate with ATG5; this conjugate has a ubiquitin-protein ligase (E3)-like activity for protein lipidation in autophagy. This conjugate also associates with innate immune response proteins such as RIG-I and VISA, inhibiting type I interferon production and permitting viral replication in host cells. ATG12 has also been shown to interact with ATG10 in human embryonic kidney cells in the presence of ATG7.There are at least two isoforms of ATG12.|
|Preservative & Stabilisers||0.02% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-ATG12 (Internal Region) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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