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Anti-Human FLIP L (C-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-Human FLIP L (C-Terminal) Antibody  ABD10046
    Western blot analysis of whole cell lysates from HeLa (H), Jurkat (J) and K562 cell lines probed with Rabbit anti Human FLIP
  • ICC - Anti-Human FLIP L (C-Terminal) Antibody  ABD10046
    Immunocytochemical staining of Jurkat cells with Rabbit anti Human FLIP
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O15519
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 55344 Da
Additional Information
Purification Antisera to FLIP were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.
Immunogen Peptide at C-terminus of human FLIPL
Shelf Life 18 months from date of despatch.
Gene ID 8837
Other Names CASP8 and FADD-like apoptosis regulator, Caspase homolog, CASH, Caspase-eight-related protein, Casper, Caspase-like apoptosis regulatory protein, CLARP, Cellular FLICE-like inhibitory protein, c-FLIP, FADD-like antiapoptotic molecule 1, FLAME-1, Inhibitor of FLICE, I-FLICE, MACH-related inducer of toxicity, MRIT, Usurpin, CASP8 and FADD-like apoptosis regulator subunit p43, CASP8 and FADD-like apoptosis regulator subunit p12, CFLAR, CASH, CASP8AP1, CLARP, MRIT
Target/Specificity ABD10046 recognises the 55kD FLIPL protein, a FLICE inhibitory protein.FLIP was cloned independently in a number of laboratories, and is also known as Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP has two death effector domains (DEDs) and a caspase-like domain. It interacts with FADD and caspase-8 and -10, potently inhibiting apoptosis by all known death receptors.FLIP exists in a short form (FLIPS) and a long form (FLIPL). Only FLIPL is recognised by this antibody.
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human FLIP L (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Irmler, M. et al. (1997) Inhibition of death receptor signals by cellular FLIP.
Nature 388: 190-195.

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Cat# ABD10046
(40 western blots)
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