|Application ||WB, IHC-P|
|Calculated MW||32509 Da|
|Purification||Antisera to CD253 (TRAIL) were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG prepared by ion exchange chromatography.|
|Immunogen||Peptide from C-terminus of human CD253 (TRAIL).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tumor necrosis factor ligand superfamily member 10, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, Protein TRAIL, CD253, TNFSF10, APO2L, TRAIL|
|Target/Specificity||Rabbit anti-Human CD253 antibody recognizes the ~32 kDa apoptosis related protein designated TRAIL (TNF-related apoptosis-inducing ligand) CD253 also known as TRAIL. CD253 is a type II membrane protein expressed in a variety of tissues. Receptors for TRAIL have been identified and termed DR4 and DR5 (Griffith and Lynch 1998).|
|Preservative & Stabilisers||0.02% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD253 (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Wiley, S.R. et al. (1995) Identification and characterization of a new member of the TNF family that induces apoptosis.Immunity. 3 (6): 673-82.2. Pitti, R.M. et al. (1996) Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family.J Biol Chem. 271 (22): 12687-90.
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