|Application ||WB, IHC-P|
|Calculated MW||33233 Da|
|Purification||Antisera to human MyD88 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Synthetic peptide corresponding to amino acids 233-248 of MyD88|
|Shelf Life||18 months from date of despatch.|
|Other Names||Myeloid differentiation primary response protein MyD88, MYD88|
|Target/Specificity||ABD10060 recognises human MyD88, an adaptor molecule involved in the interleukin-1 (IL-1) signalling pathway. MyD88 is also considered to be a general adaptor/regulator protein of the Toll/IL-R1 receptor family.|
|Preservative & Stabilisers||0.02% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-MyD88 (aa233-248) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
2. Hodges, A. et al. (2007) Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication.Nat Immunol. 8: 569-77.1. Medzhitov, R. et al. (1998) MyD88 is an adaptor protein in the hToll/IL-1 receptor family signaling pathways.Mol. Cell. 2: 253-8.
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