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Anti-AKT1 (N-Terminal) Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-AKT1 (N-Terminal) Antibody  ABD10080
    Western blot analysis of human liver cell lysate probed with Rabbit anti Human Akt1 at 1(A) and 2(B) ug/ml
  • IHC - Anti-AKT1 (N-Terminal) Antibody  ABD10080
    Immunohistochemical staining of human liver with Rabbit anti Human Akt1
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P31749
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 55686 Da
Additional Information
Other Species Rat,M
Purification Antisera to human Akt1 (NT) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen A 16 amino acid peptide located near the human Akt1 amino-terminus.
Shelf Life 18 months from date of despatch.
Gene ID 207
Other Names RAC-alpha serine/threonine-protein kinase,, Protein kinase B, PKB, Protein kinase B alpha, PKB alpha, Proto-oncogene c-Akt, RAC-PK-alpha, AKT1, PKB, RAC
Target/Specificity Rabbit anti-AKT1 antibody recognizes the N-terminal region of Akt1, also known as RAC-alpha serine/threonine-protein kinase, protein kinase B alpha or Proto-oncogene c-Akt. AKT1 is a 480 amino acid ~48 kDa protein kinase forming part of the PI3K-Akt signalling pathway, known to regulate cell growth, proliferation and survival. The PI3K-Akt1 pathway is negatively regulated by the tumour suppressor PTEN (Cantley et al.1999). Excessive Akt1 activation can lead to the formation of malignant tumours, and has been associated with prostate cancer progression (Sun et al.2001).
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-AKT1 (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Stern, D.F. (2004) More than a marker... Phosphorylated Akt in prostate carcinoma.
Clin Cancer Res. 10: 6407-10.

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Cat# ABD10080
(40 western blots)
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