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Anti-RHEB Antibody

Rabbit Anti-Human Polyclonal Antibody

  • WB - Anti-RHEB Antibody  ABD10081
    Western blot analysis of mouse brain lysate probed with Rabbit anti Human Rheb at 1(A) 2(B) and 4(C) ug/ml
  • IHC - Anti-RHEB Antibody  ABD10081
    Immunohistochemical staining of mouse brain with Rabbit anti Human Rheb
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15382
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 20497 Da
Additional Information
Other Species Rat,M
Purification Antisera to human Rheb (IN) were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Immunogen A 15 amino acid peptide located in the internal region of human Rheb.
Shelf Life 18 months from date of despatch.
Gene ID 6009
Other Names GTP-binding protein Rheb, Ras homolog enriched in brain, RHEB, RHEB2
Target/Specificity ABD10081 recognises Ras homologue enriched in brain (Rheb) a 17kDa G-protein and evolutionarily conserved Ras family member, widely expressed in tissues other than the brain.Compared with many small GTPases, Rheb is unique since it exists in a highly activated state in mammalian cells. Rheb also plays an important part in regulating the TOR signally pathway.Although Rheb is expressed at relatively high levels in the adult cortex, it can be rapidly induced in brain neurons by synaptic activity. Following a seizure, it is transiently induced in the hippocampus.
Preservative & Stabilisers 0.02% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-RHEB Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Zhang, Y. et al. (2003) Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins.
Nature Cell Biology. 5: 578-581.2. Yamagata, K. et al. (1994) Rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein.
J. Biol. Chem. 269: 16333-16339.

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Cat# ABD10081
(40 western blots)
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