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>   home   >   Products   >   Primary Antibodies   >   Microbiology   >   Anti-Human CD66acd Antibody, clone YTH71.3    

Anti-Human CD66acd Antibody, clone YTH71.3

Rat Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD66acd Antibody, clone YTH71.3  ABD10091
    Staining of human peripheral blood granulocytes with Rat anti Human CD66acd
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P40198
Other Accession P40199, P13688
Reactivity Human
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names YTH71.3
Calculated MW 27091 Da
Additional Information
Other Species Rh
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Human lymphocytes
Shelf Life 18 months from date of despatch.
Gene ID 1084
Other Names Carcinoembryonic antigen-related cell adhesion molecule 3, Carcinoembryonic antigen CGM1, CD66d, CEACAM3, CD66D, CGM1
Target/Specificity Rat anti-Human CD66acd antibody, clone YTH71.3 recognizes 3 members of the human CD66 family, namely CD66a, also known as Carcinoembryonic antigen-related cell adhesion molecule 1, Biliary glycoprotein 1 or CEACAM1. Clone YTH71.3 also recognizes CD66c, known as Carcinoembryonic antigen-related cell adhesion molecule 6 or Non-specific crossreacting antigen. In addition the clone also recognizes CD66d which in turn is also known as Carcinoembryonic antigen-related cell adhesion molecule 3 or CGM1 (Wattet al.1991). CD66 family members are single pass, type 1 membrane glycoproteins bearing a single V-type Ig-like domain and a varying number of C2-type Ig-like domains. Clone YTH71.3 recognizes epitopes in the N-terminal domain of these CD66 family members.CD66 members are expressed by human neutrophils and cells of the colon where it is down regulated in some cases of colon carcinoma (Neumaier
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD66acd Antibody, clone YTH71.3 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Watt, S.M. et al. (1991) CD66 identifies a neutrophil-specific epitope within the haematopoietic system that is expressed by members of the carcinoembryonic family of adhesion molecules.
Blood 78: 63-74. 2. Skubitz, K.M. et al. (1993) In Leucocyte Typing V. White Cell Differentiation Antigen p. 889 - 899 Volume One.
Oxford University Press, Oxford. 3. Jonker, M. et al. (1989) Reactivity of Mab specific for human CD markers with Rhesus monkey leucocytes.
Leucocyte Typing IV p 1058-1063 Oxford University Press, Oxford. 4. N'Guessan, P.D. et al. (2007) The UspA1 protein of Moraxella catarrhalis induces CEACAM-1-dependent apoptosis in alveolar epithelial cells.
J Infect Dis. 195: 1651-60. 5. Hill, D.J. and Virji, M. (2003) A novel cell-binding mechanism of Moraxella catarrhalis ubiquitous surface protein UspA: specific targeting of the N-domain of carcinoembryonic antigen-related cell adhesion molecules by UspA1.
Mol Microbiol. 48: 117-29. 6. Bradley, C.J. et al. (2005) Critical determinants of the interactions of capsule-expressing Neisseria meningitidis with host cells: the role of receptor density in increased cellular targeting via the outer membrane Opa proteins
Cell Microbiol. 7: 1490-503.

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Cat# ABD10091
(40 western blots)
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