|Application ||FC, IP|
|Calculated MW||114489 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||alpha9 integrin transfected lambda cells.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Integrin alpha-9, Integrin alpha-RLC, ITGA9|
|Target/Specificity||Mouse anti-Human Integrin alpha 9 beta 1 antibody, clone Y9A2 recognizes the human alpha9 integrin, a 140kD glycoprotein expressed as a heterodimer in association with the beta1 integrin. The alpha9 integrin is expressed by epithelial cells, including airway epithelial cells. Mouse anti-Human Integrin alpha 9 beta 1 antibody, clone Y9A2 inhibits adhesion of alpha9 expressing cells to N-terminal osteopontin.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Integrin alpha 9 beta 1 Antibody, clone Y9A2 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Wang, A. et al. (1996) Differential regulation of airway epithelial integrins by growth factors.Am. J. Respir, Cell. Mol. Biol. 15: 664-672. 2. Smith, L. L. et al. (1996) Osteopontin N-terminal domain contains a cryptic adhesive sequence recognised by alpha9 beta1 integrin.J. Biol. Chem. 271: 28485-28491. 3. Yokosaki, Y. et al. (1996) Differential effects of the integrins alpha9beta1, alphavbeta3, and alphavbeta6 on cell proliferative responses to tenascin. Roles of the beta subunit extracellular and cytoplasmic domains.J. Biol. Chem. 271: 24144-24150. 4. Sime, W. et al. (2009) Human mast cells adhere to and migrate on epithelialand vascular basement membrane laminins LM-332 and LM-511 via alpha3beta1integrin. J Immunol. 183: 4657-65.
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