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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   Anti-Human Retinoblastoma Gene Protein Antibody, clone IF8    

Anti-Human Retinoblastoma Gene Protein Antibody, clone IF8

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P06400
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names IF8
Calculated MW 106159 Da
Additional Information
Immunogen Recombinant human retinoblastoma gene protein
Shelf Life 12 months from date of reconstitution.
Gene ID 5925
Other Names Retinoblastoma-associated protein, p105-Rb, pRb, Rb, pp110, RB1
Target/Specificity Mouse anti-Human Retinoblastoma Gene Protein antibody, clone IF8 recognizes the human retinoblastoma (Rb) gene product. Rb is a tumor suppressor protein which may act upon the transcription factor ATF-2.Rb gene mutation may be associated with tumor development.
Preservative & Stabilisers 15mM Sodium Azide
Storage Storage at 4℃ or at -20℃.
PrecautionsAnti-Human Retinoblastoma Gene Protein Antibody, clone IF8 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Bártek, J. et al. (1992) Cellular localization and T antigen binding of the retinoblastoma protein.
Oncogene. 7: 101-8. 2. Markiewicz, E. et al. (2002) Lamin A/C Binding Protein LAP2a Is Required for Nuclear Anchorage of Retinoblastoma Protein
Mol Biol Cell. 13: 4401-13. 3. Paggi, M.G. et al. (1994) Defective human retinoblastoma protein identified by lack of interaction with the E1A oncoprotein.
Cancer Res. 54: 1098-104. 4. Reynisdóttir, I. et al. (1999) The retinoblastoma protein alters the phosphorylation state of polyomavirus large T antigen in murine cell extracts and inhibits polyomavirus origin DNA replication.
J Virol. 73: 3004-13. 5. Zamanian, M. and La Thangue, N.B. (1993) Transcriptional repression by the Rb-related protein p107.
Mol Biol Cell. 4: 389-96. 6. Fåhraeus, R. et al. (1996) Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A.
Curr Biol. 6: 84-91. 7. Ahuja, H.G. et al. (1991) Abnormalities of the retinoblastoma gene in the pathogenesis of acute leukemia.
Blood. 78: 3259-68.

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Cat# ABD10113
(40 western blots)
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