|Application ||FC, IP|
|Calculated MW||33077 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||NS-O cells transfected with human CD20.|
|Shelf Life||18 months from date of despatch.|
|Other Names||B-lymphocyte antigen CD20, B-lymphocyte surface antigen B1, Bp35, Leukocyte surface antigen Leu-16, Membrane-spanning 4-domains subfamily A member 1, CD20, MS4A1, CD20|
|Target/Specificity||Mouse anti-Human CD20 antibody, clone AT80, a mouse anti-human CD20 antibody, recognizes the human CD20 cell surface antigen, a ~33-37 kDa non-glycosylated phosphoprotein. The CD20 antigen is expressed during pre-B-cell development. It is present on both resting and activated B-cells but is lost prior to terminal B-cell differentiation into plasma cells. Mouse anti-Human CD20 antibody, clone AT80 recognizes an extracellular domain of CD20.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD20 Antibody, clone AT80 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Zarkesh-Esfahani, H. et al. (2001) High-dose leptin activates human leukocytes via receptor expression on monocytes.J Immunol. 167 (8): 4593-9. 2. Cragg, M.S. et al. (2003) Complement-mediated lysis by anti-CD20 mAb correlates with segregation into lipid rafts.Blood. 101 (3): 1045-52. 3. Chan, H.T. (2003) CD20-induced lymphoma cell death is independent of both caspases and itsredistribution into triton X-100 insoluble membrane rafts.Cancer Res. 2003 Sep 1;63(17):5480-9. 4. Polyak, M.J. & Deans, J.P. (2002) Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.Blood. 99 (9): 3256-62.
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