|Application ||IHC-F, FC, IP|
|Calculated MW||57742 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Other Names||Nectin-2, Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Poliovirus receptor-related protein 2, CD112, PVRL2, HVEB, PRR2|
|Target/Specificity||Mouse anti-Human CD112 antibody, clone R2-525 recognizes CD112, also known as Poliovirus Receptor Related 2, PRR2 or Nectin-2, a surface molecule originally reported to be homologous to CD155, the poliovirus receptor (Lopezet al.1998). PRR2 expression is restricted to the myelo-monocytic and megakaryocytic lineages. PRR2 expression has also been detected on haematopoeitic progenitors expressing CD34.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD112 Antibody, clone R2-525 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Lopez, M. et al. (1998) The human poliovirus receptor related 2 protein is a new hematopoietic/endothelial homophilic adhesion molecule.Blood. 92 (12): 4602-11. 2. Goyert, S.M. (1998) White cell differentiation antigens, Myeloid Antigens: section report.Leucocyte typing VI. Kishimoto, T. et al. eds (Garland Publishing Inc. New York) p. 956-957 3. Cocchi F, et al. (2000) Cell-to-cell spread of wild-type herpes simplex virus type 1, but not of syncytial strains, is mediated by the immunoglobulin-like receptors that mediate virion entry, nectin1 (PRR1/HveC/HIgR) and nectin2 (PRR2/HveB).J Virol. 74 (8): 3909-17.
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