|Application ||WB, IHC-P, IHC-F, E, IP|
|Calculated MW||34830 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Synthetic peptide corresponding to amino acids 301-318 of rat aquaporin 4.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4, AQP4|
|Target/Specificity||Mouse anti-Aquaporin 4 antibody, clone 3D2 recognizes an epitope within the cytoplasmic domain of the water-specific channel aquaporin 4 (also known as AQP4). Aquaporin 4 is located in various tissues including the gastro-intestinal tract, kidney and brain.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Aquaporin 4 Antibody, clone 3D2 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Nagy, G. et al. (2002) Development and characterisation of a monoclonal antibody family againstaquaporin 1 (AQP1) and aquaporin 4 (AQP4).Pathol. Oncol. Res. 8: 115-124. 2. Bodis, B. et al. (2001) Active water selective channels in the stomach: investigation of aquaporins after ethanol and capsaicin treatment in rats. J. Physiol. 95: 271-275. 3. Badaut, J. (2006) Abnormalities in the pattern of AQP4 immunoreactivity.FASEB J. 20: 2423-4 4. Meshorer, E. et al. (2005) Chronic cholinergic imbalances promote brain diffusion and transport abnormalities.FASEB J. 19: 910-22. 5. Frydenlund, D.S. et al. (2006) Temporary loss of perivascular aquaporin-4 in neocortex after transient middle cerebral artery occlusion in mice.Proc Natl Acad Sci U S A. 103: 13532-6. 6. Mao, X. et al. (2006) Aquaporin 4 changes in rat brain with severe hydrocephalus.Eur J Neurosci. 23: 2929-36.
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