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Anti-Aquaporin 4 Antibody, clone 3D2

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P55087
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 3D2
Calculated MW 34830 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Synthetic peptide corresponding to amino acids 301-318 of rat aquaporin 4.
Shelf Life 18 months from date of despatch.
Gene ID 361
Other Names Aquaporin-4, AQP-4, Mercurial-insensitive water channel, MIWC, WCH4, AQP4
Target/Specificity Mouse anti-Aquaporin 4 antibody, clone 3D2 recognizes an epitope within the cytoplasmic domain of the water-specific channel aquaporin 4 (also known as AQP4). Aquaporin 4 is located in various tissues including the gastro-intestinal tract, kidney and brain.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Aquaporin 4 Antibody, clone 3D2 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Nagy, G. et al. (2002) Development and characterisation of a monoclonal antibody family againstaquaporin 1 (AQP1) and aquaporin 4 (AQP4).
Pathol. Oncol. Res. 8: 115-124. 2. Bodis, B. et al. (2001) Active water selective channels in the stomach: investigation of aquaporins after ethanol and capsaicin treatment in rats.
J. Physiol. 95: 271-275. 3. Badaut, J. (2006) Abnormalities in the pattern of AQP4 immunoreactivity.
FASEB J. 20: 2423-4 4. Meshorer, E. et al. (2005) Chronic cholinergic imbalances promote brain diffusion and transport abnormalities.
FASEB J. 19: 910-22. 5. Frydenlund, D.S. et al. (2006) Temporary loss of perivascular aquaporin-4 in neocortex after transient middle cerebral artery occlusion in mice.
Proc Natl Acad Sci U S A. 103: 13532-6. 6. Mao, X. et al. (2006) Aquaporin 4 changes in rat brain with severe hydrocephalus.
Eur J Neurosci. 23: 2929-36.

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Cat# ABD10149
(40 western blots)
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