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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human Granzyme B Antibody, clone GB7    

Anti-Human Granzyme B Antibody, clone GB7

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P10144
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names GB7
Calculated MW 27716 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen Recombinant Granzyme B.
Shelf Life 18 months from date of despatch.
Gene ID 3002
Other Names Granzyme B,, C11, CTLA-1, Cathepsin G-like 1, CTSGL1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, HLP, SECT, T-cell serine protease 1-3E, GZMB, CGL1, CSPB, CTLA1, GRB
Target/Specificity Mouse anti-Human Granzyme B antibody, clone GB7 recognizes the serine protease Granzyme B, which is expressed within the granules of cytolytic lymphocytes (CTLs)Granzyme B plays a key role in the induction of apoptosis by CTLs. After delivery to the target cell Granzyme B activates the cascade of caspases that finally results in cell death.Mouse anti-Human Granzyme B antibody, clone GB7 has been reported to be suitable for Western Blotting.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Granzyme B Antibody, clone GB7 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Kummer, J. A. et al. (1993) Production and characterisation of monoclonal antibodies raised against recombinant human granzymes A and B and showing cross reactions with the natural proteins.
J. Immunol. Methods. 163: 77-83. 2. Nield, L.E. et al. (2002) Endocardial fibroelastosis associated with maternal anti-Ro and anti-La antibodies in the absence of atrioventricular block.
J Am Coll Cardiol. 40: 796-802. 3. Himmelein, S. et al. (2015) Latent herpes simplex virus 1 infection does not induce apoptosis in human trigeminal Ganglia.
J Virol. 89 (10): 5747-50.

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Cat# ABD10151
(40 western blots)
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