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Anti-Mouse CD94 Antibody, clone 18d3

Rat Anti-Mouse Monoclonal Antibody

  • FC - Anti-Mouse CD94 Antibody, clone 18d3  ABD10159
    Staining of mouse peripheral blood lymphocytes with Rat anti Mouse CD94: Alexa Fluor® 488
  • FC - Anti-Mouse CD94 Antibody, clone 18d3  ABD10159
    Staining of mouse peripheral blood lymphocytes probed with Rat anti Mouse CD94 : RPE
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O54707
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names 18d3
Calculated MW 20808 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen CHO cells transfected with B6 allele of CD94
Shelf Life 18 months from date of despatch.
Gene ID 16643
Other Names Natural killer cells antigen CD94, Killer cell lectin-like receptor subfamily D member 1, CD94, Klrd1, Cd94
Target/Specificity Rat anti-Mouse CD94 antibody, clone 18d3 recognizes murine CD94, a 70kDa cell surface glycoprotein expressed primarily by mouse natural killer (NK) cells. The murine CD94 molecule forms heterodimers with NKG2A, C or E subunits to form the CD94/NKG2 receptor.In mice the CD94/NKG2 receptor recognizes Qa-1b, a non-classical MHC class 1 molecule. CD94/NKG2 receptors may play an important role in self-tolerance of NK cells during fetal and neonatal life. N.B. Recent reports suggest that DBA/2J mice do not express cell surface CD94/NKG2A receptors (Vanceet al.2002).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse CD94 Antibody, clone 18d3 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Vance, R.E. et al. (2002) Implications of CD94 deficiency and monoallelic NKG2A expression for natural killer cell development and repertoire function.
Proc. Natl. Acad. Sci. USA. 99:868-873. 2. Vance, R.E. et al. (1999) Recognition of the Class Ib Molecule Qa-1b by Putative Activating Receptors CD94/NKG2C and CD94/NKG2E on Mouse Natural Killer Cells.
J. Exp. Med. 190:1801-1812. 3. Chattopadhyay, al. (2008) Implication for the CD94/NKG2A-Qa-1 system in the generation and function of ocular-induced splenic CD8+ regulatory T cells.
Int. Immunol. 20: 509-516. 4. Kawamura. H. et al. (2005) Amelioration of acute graft-versus-host disease by NKG2A engagement on donor T cells.
Eur. J. Immunol. 35: 2358-66.

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Cat# ABD10159
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