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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Human MAdCAM-1 Antibody, clone 17F5    

Anti-Human MAdCAM-1 Antibody, clone 17F5

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13477
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 17F5
Calculated MW 40155 Da
Additional Information
Other Species Camel
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Recombinant soluble MAdCAM-1-fc fusion protein.
Shelf Life 18 months from date of despatch.
Gene ID 8174
Other Names Mucosal addressin cell adhesion molecule 1, MAdCAM-1, hMAdCAM-1, MADCAM1
Target/Specificity Mouse anti-Human MAdCAM-1 antibody, clone 17F5 recognizes human mucosal addressin cell adhesion molecule 1 (MAdCAM-1) a ~60 kDa transmembrane protein that belongs to the immunoglobulin superfamily. MAdCAM-1 is strongly expressed on mucosal lymphoid tissue and high endothelial venules of Peyer's patches. Human MAdCAM-1 interacts with the beta 7 integrin LPAM-1 (alpha4beta7), CD62L, and VLA-4 (alpha4beta1) and is involved in lymphocyte trafficking, Clone 17F5 recognizes the mucin domain of MAdCAM-1. This antibody does not block the function of MAdCAM-1 (Leung, E. et al.2004).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human MAdCAM-1 Antibody, clone 17F5 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Leung, E. et al. (1996) Cloning of the mucosal addressin MAdCAM-1 from human brain: identification of novel alternatively spliced transcripts.
Immunol Cell Biol. 74 (6): 490-6. 2. Leung, E. et al. (2004) Bioassay detects soluble MAdCAM-1 in body fluids.
Immunol Cell Biol. 82 (4): 400-9. 3. AL-Mohammed Salem K.T. (2012) Adhesion Molecules and the Cellular Population of the Normal Camel (Camelus dromedaries) Mammary Glands
The Open Veterinary Science Journal. 6 (1): 15-22. 4. Guerra-Pérez N et al. (2015) Retinoic acid imprints a mucosal-like phenotype on dendritic cells with an increased ability to fuel HIV-1 infection.
J Immunol. 194 (5): 2415-23.

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Cat# ABD10162
(40 western blots)
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