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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human CD261 Antibody, clone DR-4-02    

Anti-Human CD261 Antibody, clone DR-4-02

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD261 Antibody, clone DR-4-02  ABD10163
    Staining of HeLa cells with Mouse anti Human CD261: Alexa Fluor® 488
  • FC - Anti-Human CD261 Antibody, clone DR-4-02  ABD10163
    Staining of HeLa cells with Mouse anti Human CD261
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00220
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names DR-4-02
Calculated MW 50089 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen Fusion protein containing the extracellular region of CD261 (DR4).
Shelf Life 18 months from date of despatch.
Gene ID 8797
Other Names Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TNF-related apoptosis-inducing ligand receptor 1, TRAIL receptor 1, TRAIL-R1, CD261, TNFRSF10A, APO2, DR4, TRAILR1
Target/Specificity Mouse anti-Human CD261 antibody, clone DR-4-02 recognizes human death receptor 4 (DR4), also known as CD261 or TRAIL- R1. DR4 is a type I transmembrane protein of 468 amino acids, which is expressed in most human tissues including spleen, peripheral blood leucocytes, thymus and in a variety of tumour-derived cell lines. DR4 plays a role in inducing cell death. The binding of TRAIL to DR4 triggers the activation of pro-caspases 8 and 10, leading to apoptosis.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD261 Antibody, clone DR-4-02 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Cosgrove, C. et al. (2013) Early and nonreversible decrease of CD161++/MAIT cells in HIV infection.
Blood. 121: 951-61. 2. Crescenzi, E. et al. (2011) NF-?B-dependent cytokine secretion controls Fas expression on chemotherapy-induced premature senescent tumor cells.
Oncogene. 30: 2707-17. 3. Zhang, Y. and Zhang, B. (2008) TRAIL resistance of breast cancer cells is associated with constitutive endocytosis of death receptors 4 and 5.
Mol Cancer Res. 6: 1861-71.

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$ 290.00
$ 54.00
Cat# ABD10163
1 Formats Available
Availability: 5-7days
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