|Calculated MW||33068 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tissue factor, TF, Coagulation factor III, Thromboplastin, CD142, F3|
|Target/Specificity||Mouse anti-Human CD142 antibody, clone CLB/TF-5 recognizes human CD142, a 45kD cell surface glycoprotein which is otherwise known as Tissue Factor (TF). CD142 expression can be induced on monocytes, macrophages and endothelial cells by various stimuli including interleukin 1, tumour necrosis factor and endotoxin. CD142 initiates the blood clotting cascade by binding coagulation factor VIIa, which activates factor IX or factor X by specific limited proteolysis. CD142 also plays an important role in inflammation, angiogenesis, and the pathophysiology of atherosclerosis and cancer.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or -20℃.|
|Precautions||Anti-Human CD142 Antibody, clone CLB/TF-5 (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. van der Putten, R.F. et al. (2005) High-affinity antibodies in a new immunoassay for plasma tissue factor: reduction in apparent intra-individual variation. Clin. Chem. Lab. Med. 43:1386 – 1391. 2. Mobarrez, F. et al. (2010) A multicolor flow cytometric assay for measurement of platelet-derived microparticles.Thromb Res. 125: e110-6. 3. Tehrani, S. et al. (2010) Atorvastatin has antithrombotic effects in patients with type 1 diabetes and dyslipidemia.Thromb Res. 126: e225-31. 4. Aass, H.C. et al. (2011) Fluorescent particles in the antibody solution result in false TF- and CD14-positive microparticles in flow cytometric analysis.Cytometry A. 79: 990-9. 5. Trummer, A. et al. (2008) Isotype controls in phenotyping and quantification of microparticles: a major source of error and how to evade it.Thromb Res. 122: 691-700.
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