|Application ||FC, E|
|Calculated MW||33068 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tissue factor, TF, Coagulation factor III, Thromboplastin, CD142, F3|
|Target/Specificity||Mouse anti-Human CD142 antibody, clone CLB/TF-1 recognizes human CD142, a 45 kDa cell surface glycoprotein which is otherwise known as Tissue Factor (TF). CD142 expression can be induced on monocytes, macrophages and endothelial cells by various stimuli including interleukin 1, tumour necrosis factor and endotoxin. CD142 initiates the blood clotting cascade by binding coagulation factor VIIa, which activates factor IX or factor X by specific limited proteolysis. CD142 also plays an important role in inflammation, angiogenesis, and the pathophysiology of atherosclerosis and cancer.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD142 Antibody, clone CLB/TF-1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. van der Putten, R.F. et al. (2005) High-affinity antibodies in a new immunoassay for plasma tissue factor: reduction in apparent intra-individual variation. Clin. Chem. Lab. Med. 43:1386 – 1391. 2. van der Putten, R.F. et al. (2005) State and diagnostic value of plasma tissue factor in early-hospitalised patients with chest pain. Br. J. Haematol. 131:91-99.
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