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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Human CD272 Antibody, clone MIH26    

Anti-Human CD272 Antibody, clone MIH26

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD272 Antibody, clone MIH26  ABD10180
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD272
  • FC - Anti-Human CD272 Antibody, clone MIH26  ABD10180
    Staining of human peripheral blood lymphocytes with Mouse anti Human CD272
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z6A9
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a
Clone Names MIH26
Calculated MW 32834 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen BTLA - transfected L cells.
Shelf Life 18 months from date of despatch.
Gene ID 151888
Other Names B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein, CD272, BTLA
Target/Specificity Mouse anti-Human CD272 antibody, clone MIH26 detects human CD272, also known as B- and T-lymphocyte attenuator (BTLA). CD272 is a type I transmembrane glycoprotein which is structurally and functionally related to cytotoxic T lymphocyte antigen-4 (CTLA-4), and programmed death-1 (PD-1). CD272 is a T-cell inhibitory receptor that regulates T cell activation through its interaction with herpes virus entry mediator (HVEM), a co-stimulator receptor of the TNFR family. CD272 may negatively regulate T-cell dependent autoimmune reaction, and polymorphisms in its gene have been associated with Rheumatoid Arthritis.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD272 Antibody, clone MIH26 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Otsuki, N. et al. (2006) Expression and function of the B and T lymphocyte attenuator (BTLA/CD272) on human T cells.
Biochem Biophys Res Commun. 344 (4): 1121-7. 2. Lin, S.C. et al. (2006) Association of a BTLA gene polymorphism with the risk of rheumatoid arthritis.
J Biomed Sci. 13 (6): 853-60.1. Zeng, C. et al. (2005) BTLA, a new inhibitory B7 family receptor with a TNFR family ligand.
Cell Mol Immunol. 2 (6): 427-32.

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Cat# ABD10180
(40 western blots)
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