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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human CD137 Antibody, clone JG1.6A    

Anti-Human CD137 Antibody, clone JG1.6A

Rat Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q07011
Reactivity Human
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names JG1.6A
Calculated MW 27899 Da
Additional Information
Other Species Cynomolgus Pr
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Recombinant human CD137-Fc
Shelf Life 18 months from date of despatch.
Gene ID 3604
Other Names Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137, TNFRSF9, CD137, ILA
Target/Specificity Rat anti-Human CD137 antibody, clone JG1.6A recognizes human CD137, an 83kD type I integral membrane protein, otherwise known as 4-1BB. The CD137 molecule is primarily expressed on activated T-cells. It is a costimulatory member of the tumour necrosis receptor family and is reported to regulate T-cell activation and proliferation.Rat anti-Human CD137 antibody, clone JG1.6A has been reported for use in functional studies.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD137 Antibody, clone JG1.6A is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Pollok, K.E. et al. (1993) Inducible T cell antigen 4-1BB. Analysis of expression and function.
J. Immunol. 150:771 – 781.2. Alderson, M.R. et al. (1994) Molecular and biological characterization of human 4-1BB and its ligand.
Eur. J. Immunol. 24:2219-2227.3. Schwarz, H. et al. (1997) CD137, a member of the tumor necrosis factor receptor family, is located on chromosome 1p36, in a cluster of related genes, and colocalizes with several malignancies.
Biochem. Biophys. Res. Commun. 235:699-703.4. Cannons, J.L. et al. (2001) 4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy.
J. Immunol.167:1313-1324.

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Cat# ABD10181
(40 western blots)
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