|Application ||FC, E|
|Calculated MW||27899 Da|
|Other Species||Cynomolgus Pr|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Recombinant human CD137-Fc|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tumor necrosis factor receptor superfamily member 9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA, CD137, TNFRSF9, CD137, ILA|
|Target/Specificity||Rat anti-Human CD137 antibody, clone JG1.6A recognizes human CD137, an 83kD type I integral membrane protein, otherwise known as 4-1BB. The CD137 molecule is primarily expressed on activated T-cells. It is a costimulatory member of the tumour necrosis receptor family and is reported to regulate T-cell activation and proliferation.Rat anti-Human CD137 antibody, clone JG1.6A has been reported for use in functional studies.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD137 Antibody, clone JG1.6A is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Pollok, K.E. et al. (1993) Inducible T cell antigen 4-1BB. Analysis of expression and function. J. Immunol. 150:771 – 781.2. Alderson, M.R. et al. (1994) Molecular and biological characterization of human 4-1BB and its ligand. Eur. J. Immunol. 24:2219-2227.3. Schwarz, H. et al. (1997) CD137, a member of the tumor necrosis factor receptor family, is located on chromosome 1p36, in a cluster of related genes, and colocalizes with several malignancies. Biochem. Biophys. Res. Commun. 235:699-703.4. Cannons, J.L. et al. (2001) 4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy. J. Immunol.167:1313-1324.
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