|Application ||WB, IHC-F, IF|
|Calculated MW||480410 Da|
|Immunogen||A synthetic peptide corresponding to amino acids from the spectrin-binding domain of human ankyrin G|
|Shelf Life||18 months from date of despatch.|
|Other Names||Ankyrin-3, ANK-3, Ankyrin-G, ANK3|
|Target/Specificity||ABD10190 is specific for ankyrin G and reacts with a region within the spectrin binding domain. In Western blotting it detects the 190 kDa isoform.Ankyrins are a family of spectrin-binding protein that couple the spectrin/actin cytoskeletal network to the cytoplasmic domains of integral membrane proteins which include channels such as the anion exchanger, voltage-dependent sodium channel and the Na/K ATPase. 3 forms of ankyrin G exists, 190 kDa, 270 kDa and 480 kDa, that are localized in the axonal intial segments and the nodes of Ranvier of myelinated axons where fluxes of action potential occur and ion channels are enriched.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Ankyrin G Antibody, clone 463 is for research use only and not for use in diagnostic or therapeutic procedures.|
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