Anti-Parathyroid Hormone Receptor 2 (Extracellular Domain 1) Antibody
Rabbit Anti-Human Polyclonal Antibody
|Calculated MW||62236 Da|
|Purification||Ig fraction prepared by ammonium sulphate precipitation|
|Immunogen||Synthetic peptide corresponding to the amino acids 99 - 116 of the parathyroid hormone receptor 2 molecule.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Parathyroid hormone 2 receptor, PTH2 receptor, PTH2R, PTHR2|
|Target/Specificity||ABD10195 is specific for the extracellular domain 1 of parathyroid hormone receptor 2. A member of the G-protein coupled receptor family, particularly abundant in the brain and pancreas .It may be responsible for PTH effects in a number of physiological systems and may play a significant role in pancreatic function. Binds parathyroid hormone, but shows very low affinity for PTHrP. This molecule is expressed in only a few tissues, and its structure and physiologic significance are poorly characterized. Type 2 receptor, is coupled to adenylyl cyclase, ligand binding induces a rise in intracellular concentration of cyclic AMP. PTH-Rec 2 (99-116) 100%PTH-Rec 1 (63-82) 0.06%PTH-Rec 1 (562-580) 0.4%|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Parathyroid Hormone Receptor 2 (Extracellular Domain 1) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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