|Application ||WB, E|
|Clone Names||35730 (49/20)|
|Calculated MW||65402 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Recombinant peptide corresponding to the extracellular domain of human CD121a expressed in insect cell line Sf21.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-1 receptor type 1, IL-1R-1, IL-1RT-1, IL-1RT1, CD121 antigen-like family member A, Interleukin-1 receptor alpha, IL-1R-alpha, Interleukin-1 receptor type I, p80, CD121a, Interleukin-1 receptor type 1, membrane form, mIL-1R1, mIL-1RI, Interleukin-1 receptor type 1, soluble form, sIL-1R1, sIL-1RI, IL1R1, IL1R, IL1RA, IL1RT1|
|Target/Specificity||Mouse anti-human CD121a, clone 35730, recognizes interleukin-1 receptor type 1 (IL1R1). IL1RA/CD121a is widely expressed in a number of cell types including T cells and fibroblasts (Simset al.)and is involved in the activation of NF-kappa-B (Slacket al.).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human CD121a Antibody, clone 35730 (49/20) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Sims, J. et al. (1989) Cloning the interleukin 1 receptor from human T cells.Proc Natl Acad Sci U S A. 86: 8946-50.2. Slack, J. et al. (2000) Identification of two major sites in the type I interleukin-1 receptor cytoplasmic region responsible for coupling to pro-inflammatory signaling pathways.J Biol Chem. 275:4670-8.
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