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>   home   >   Products   >   Primary Antibodies   >   Anti-Folate Binding Protein Antibody, clone SF55 (BGN/1210/55)    

Anti-Folate Binding Protein Antibody, clone SF55 (BGN/1210/55)

Mouse Anti-Bovine Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02702
Reactivity Bovine
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names SF55 (BGN/1210/55)
Calculated MW 27922 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Folate binding protein from bovine milk.
Shelf Life 18 months from date of despatch.
Gene ID 516067
Other Names Folate receptor alpha, FR-alpha, Folate receptor 1, Folate-binding protein 1, FBP, Milk folate-binding protein, FOLR1
Target/Specificity Mouse anti-folate binding protein antibody, clone SF55, recognizes the folate receptor alpha, also known as folate binding protein (FBP) and Milk folate-binding protein. Folate receptor alpha is a 241 amino acid 30 kDa protein with a 19 amino acid signal peptide and a 7 amino acid c-terminal propeptide cleaved in the mature form. The folate receptor alpha has a high affinity for folate and several reduced folic acid derivatives and mediates the intracelullar delivery of 5 methyltetrahydrofolate. Membrane bound and soluble forms of a high affinity FBP have been found in kidney, placenta, serum, milk, and several cell lines.Mouse anti-folate binding protein antibody, clone SF55 can enhance STAT3 activation through binding to the folatereceptor alpha (Hansenet al.2015).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Folate Binding Protein Antibody, clone SF55 (BGN/1210/55) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Hansen, M.F. et al. (2015) Folic acid mediates activation of the pro-oncogene STAT3 via the Folate Receptor alpha.
Cell Signal. 27 (7): 1356-68.1. Henderson, G.B. (1990) Folate-binding proteins.
Annu Rev Nutr. 10: 319-35.2. Jones, M.L. & Nixon, P.F. (2002) Tetrahydrofolates are greatly stabilized by binding to bovine milk folate-binding protein.
J Nutr. 132 (9): 2690-4.

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