|Calculated MW||10963 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Recombinant human osteocalcin GST fusion protein.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Osteocalcin, Bone Gla protein, BGP, Gamma-carboxyglutamic acid-containing protein, BGLAP|
|Target/Specificity||Mouse anti-Human Osteocalcin antibody, clone 8H12F9H10 recognizes intact human and bovine osteocalcin in a 2 site assay and reacts with osteocalcin fragments corresponding to amino acids 1-19, 7-19 and 15-31 of the native molecule. It does not recognize fragments representing amino acids 20-43 or intact bovine osteocalcin.Osteocalcin (Bone Gla Protein) is a 49 amino acid single chain vitamin K dependent protein (MW 5.8 kDa), made by osteoblasts that is a major component of the non-collagenous bone matrix. Serum osteocalcin is elevated in diseases characterized by increased bone turnover such as osteoporosis, hyperparathyroidism and Paget’s disease, and low in conditions associated with low bone turnover such as hypoparathyroidism and growth hormone deficiency.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Osteocalcin Antibody, clone 8H12F9H10 is for research use only and not for use in diagnostic or therapeutic procedures.|
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