|Application ||WB, IHC-F, E|
|Calculated MW||30778 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Native Apolipoprotein-A1 from human plasma|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1, Proapolipoprotein A-I, ProapoA-I, Truncated apolipoprotein A-I, Apolipoprotein A-I(1-242), APOA1|
|Target/Specificity||Mouse anti-Human Apolipoprotein A1, clone G2 recognizes Apolipoprotein A-1 (also known as Apo-A1) , a lipid-binding protein which enables the transport of dietary lipids for storage, metabolism and secretion. Apo-A1 plays an important part in the removal of cholesterol from cells.Mouse anti-Human Apolipoprotein A1, clone G2 reacts with both free human Apo-A1 and High Density Lipoprotein (HDL) bearing Apo-A1, but does not cross-react with ApoE, ApoB or Albumin.|
|Preservative & Stabilisers||1% Dextran; 1% Mannitol|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Human Apolipoprotein A1 Antibody, clone G2 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Derbali, H. et al. (2010) Increased biglycan in aortic valve stenosis leads to the overexpression of phospholipid transfer protein via Toll-like receptor 2. Am J Pathol. 176: 2638-45. 2. Mogilenko, D.A. et al. (2012) Endogenous apolipoprotein A-I stabilizes ATP-binding cassette transporter A1 and modulates Toll-like receptor 4 signaling in human macrophages.FASEB J. 26: 2019-30. 3. Shavva, V.S. et al. (2016) PPARγ Represses Apolipoprotein A-I Gene but Impedes TNFα-Mediated ApoA-I Downregulation in HepG2 Cells.J Cell Biochem. Jan 27. [Epub ahead of print] 4. Pingitore, P. et al. (2016) Identification and characterization of two novel mutations in the LPL gene causing Type I hyperlipoproteinemiaJournal of Clinical Lipidology. 10 Mar [Epub ahead of print]
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