|Calculated MW||20187 Da|
|Shelf Life||18 months from date of despatch.|
|Other Names||Interleukin-7, IL-7, IL7|
|Target/Specificity||Rat anti-Human Interleukin-7 antibody, clone BVD10-40F6 recognizes human interleukin 7 (IL-7), also known as Lymphopoietin 1 or pre-B cell factor. IL-7 is a 177 amino acid haematopoietic growth factor stimulating primarily early B and T lymphocytes. IL- 7 is required for development of T-cells in the thymus (Plumet al.1996) and absence of the IL-7 receptor α chain (CD127) leads to a severe combined immunodeficiency condition through the lack of T-cell production (Roifmanet al.2000). IL-7 is also important post-thymically for homeostasis of naive T-cell populations and generation and survival of CD4+ memory T-cells (Kondracket al.2003).IL-7 deficiency or deficient function is also noted in immunodeficiency diseases including rheumatoid arthritis (Leonard 2005), chronic colitis (Totsukaet al.2007). multiple sclerosis through CD127 (Svejgaard 2008) and diabetes (Liet al.2011).Rat anti-Human Interleukin-7 antibody, clone BVD10-40F6 has been used sucessfully in the development of a sensitive ELISA assay as a capture reagent for human IL-7.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Store at -20℃ only.|
|Precautions||Anti-Human Interleukin-7 Antibody, clone BVD10-40F6 is for research use only and not for use in diagnostic or therapeutic procedures.|
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