|Calculated MW||48047 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Synthetic peptide corresponding to the amino acids 84 - 94 of human BMP-10 (402-412 of the unprocessed precursor) conjugated to Keyhole Limpet Haemocyanin.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Bone morphogenetic protein 10, BMP-10, BMP10|
|Target/Specificity||Intended UseTarget SpeciesHumanSpecies Cross-ReactivityTarget SpeciesCross ReactivityRatExpected from SequenceMouseExpected from SequenceN.B. Antibody reactivity and working conditions may vary between species.Product FormPurified IgG - liquid ReconstitutionPreparationPurified IgG prepared by affinity chromatography on Protein GPreservative Stabilisers0.09% Sodium Azide (NaN3)ImmunogenSynthetic peptide corresponding to the amino acids 84 - 94 of human BMP-10 (402-412 of the unprocessed precursor) conjugated to Keyhole Limpet Haemocyanin.Peptide SequenceLDKGVVTYKFKThis sequence is identical to the published sequences for human, mouse and rat BMP-10 proteins.PurityApprox. Protein ConcentrationsIgG concentration 5.0 mg/mlReagents In The KitPreparing The AntibodyTest PrincipleBuffer SolutionPhosphate buffered salineStorageStore at +4oC or at -20oC if preferred.Storage in frost-free freezers is not recommended.This product should be stored undiluted.Avoid repeated freezing and thawing as this may denature the antibody.Should this product contain a precipitate we recommend microcentrifugation before use.Shelf Life18 months from date of despatch.GO TermsGO:0010614negative regulation of cardiac muscle hypertrophy;GO:0005615extracellular space;GO:0030308negative regulation of cell growth;GO:0032924activin receptor signaling pathway;GO:0055015ventricular cardiac muscle cell development;GO:0007219Notch signaling pathway;GO:0055010ventricular cardiac muscle tissue morphogenesis;GO:0055009atrial cardiac muscle tissue morphogenesis;GO:0060347heart trabecula formation;GO:0060038cardiac muscle cell proliferation;GO:0030018Z disc;GO:0005125cytokine activity;GO:0045214sarcomere organization;GO:0008083growth factor activity;GO:0007512adult heart development;GO:0010862positive regulation of pathway-restricted SMAD protein phosphorylation;GO:0045941positive regulation of transcription;GO:0010596negative regulation of endothelial cell migration;GO:0030509BMP signaling pathway;GO:0010613positive regulation of cardiac muscle hypertrophy;GO:0033612receptor serine/threonine kinase binding;GO:0009986cell surface;GO:0060045positive regulation of cardiac muscle cell proliferation;GO:0060389pathway-restricted SMAD protein phosphorylation;UniProtO95393;Entrez GeneBMP10;AcknowledgementsRegulatoryFor research purposes only|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human BMP-10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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