|Application ||IHC-P, IHC-F, IF, E|
|Calculated MW||13948 Da|
|Purification||Purified Ig prepared by affinity chromatography on Protein G|
|Immunogen||Synthetic rat Tyr-CGRP (23-37) conjugated to gamma globulin.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Calcitonin gene-related peptide 1, Alpha-type CGRP, Calcitonin gene-related peptide I, CGRP-I, Calca, Calc|
|Target/Specificity||Goat anti-Rat Calcitonin Gene-Related Peptide antibody recognizes Calcitonin gene-related peptide, also known as CGRP, a neuropeptide that acts as a vasodilator and may play a role in migraine. Goat anti-Rat Calcitonin Gene-Related Peptide antibody reacts with both the whole molecule (amino acids 1-37) and the C-terminal fragment (23-37).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Rat Calcitonin Gene-Related Peptide Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Collins, J.J. et al (2000) Distribution and origin of secretoneurin-immunoreactive nerves in the female rat uterus.Neuroscience 95: 255-264. 2. Pritz. M.B. and Stritzel, M.E. (1988) Thalamic nuclei that project to reptilian telencephalon lack GABA and GAD immunoreactive neurons and puncta.Brain Res. 457: 154-159. 3. Pritz. M.B. and Stritzel, M.E. (1989) Reptilian dorsal column nucleus lacks GAD immunoreactive neurons.Brain Res. 503: 175-179. 4. Fan, W. et al. (2010) Structural and cellular features in metaphyseal and diaphyseal periosteum of osteoporotic rats.J Mol Histol. 41: 51-60. 5. Hamed, K. et al. (2011) Changes in cutaneous innervation in patients with chronic pain after burns. Burns. 37: 631-7 6. Brock, J.A. et al. (2007) Postnatal androgen deprivation dissociates the development of smooth muscle innervation from functional neurotransmission in mouse vas deferens.J Physiol. 581: 665-78. 7. Gnanamanickam, G.J. and Llewellyn-Smith, I.J. (2011) Innervation of the rat uterus at estrus: a study in full-thickness, immunoperoxidase-stained whole-mount preparations.J Comp Neurol. 519: 621-43. 8. Marchant, N.J. et al. (2007) Coexpression of prodynorphin and corticotrophin-releasing hormone in the rat central amygdala: evidence of two distinct endogenous opioid systems in the lateral division.J Comp Neurol. 504: 702-15. 9. Golden, J.P. et al. (2010) RET signaling is required for survival and normal function of nonpeptidergic nociceptors.J Neurosci. 30: 3983-94. 10. Ikeda, E. et al. (2009) Fully functional bioengineered tooth replacement as an organ replacement therapy.Proc Natl Acad Sci U S A. 106: 13475-80. 11. Iliff, J.J. et al. (2010) Epoxyeicosatrienoic acids are endogenous regulators of vasoactive neuropeptide release from trigeminal ganglion neurons.J Neurochem. 115: 1530-42. 12. Iliff, J.J. et al. (2009) Epoxyeicosanoids as mediators of neurogenic vasodilation in cerebral vessels.Am J Physiol Heart Circ Physiol. 296: H1352-63. 13. Tague, S.E. and Smith, P.G. (2011) Vitamin D receptor and enzyme expression in dorsal root ganglia of adult female rats: modulation by ovarian hormones.J Chem Neuroanat. 41: 1-12. 14. Zou, M. et al. (2012) Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord.Dev Biol. 364: 114-27. 14. Chucair-Elliott, A.J. et al. (2015) Degeneration and Regeneration of Corneal Nerves in Response to HSV-1 Infection.Invest Ophthalmol Vis Sci. pii: IOVS-14-15596. 15. Yu, W.M. et al. (2009) Disruption of laminin in the peripheral nervous system impedes nonmyelinating Schwann cell development and impairs nociceptive sensory function.Glia. 57: 850-9. 16. Zimmerman, A.L. et al. (2012) Monoaminergic Modulation of Spinal Viscero-Sympathetic Function in the Neonatal Mouse Thoracic Spinal CordPLoS One. 7: e47213. 17. Drummond, E.S. et al. (2013) Increased expression of cutaneous α1-adrenoceptors after chronic constriction injury in rats.J Pain. pii: S1526-5900(13)01351-5. 18. Li, Z. et al. (2014) Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in micePain. pii: S0304-3959(14)00228-0. 19. Drummond, P.D. et al. (2014) Upregulation of α1-adrenoceptors on cutaneous nerve fibres after partial sciatic nerve ligation and in complex regional pain syndrome type II.Pain. 155: 606-16. 20. Marvaldi L et al. (2015) Enhanced axon outgrowth and improved long-distance axon regeneration in sprouty2 deficient mice.Dev Neurobiol. 75 (3): 217-31. 21. Pitzer, C. et al. (2008) Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis.Brain. 131: 3335-47. 22. Chucair-Elliott, A.J. et al. (2015) Degeneration and Regeneration of Corneal Nerves in Response to HSV-1 Infection.Invest Ophthalmol Vis Sci. pii: IOVS-14-15596. 23. Weir, K.A. and Lunam, C.A. (2006) Immunohistochemical study of cutaneous nerves in the emu.Cell Tissue Res. 326: 697-705. 24. Valtcheva, M.V. et al. (2015) Enhanced non-peptidergic intraepidermal fiber density and an expanded subset of chloroquine-responsive trigeminal neurons in a mouse model of dry skin itch.J Pain. pii: S1526-5900(15)00043-7. 25. Payne, S.C. et al. (2015) Regeneration of sensory but not motor axons following visceral nerve injury.Exp Neurol. 266C: 127-142. 26. Van Steenwinckel, J. et al. (2015) Stromal cell-derived CCL2 drives neuropathic pain states through myeloid cell infiltration in injured nerve.Brain Behav Immun. 45: 198-210. 27. Wong, A.W. et al. (2015) Neurite outgrowth in normal and injured primary sensory neurons reveals different regulation by nerve growth factor (NGF) and artemin.Mol Cell Neurosci. 65: 125-134. 28. Watanabe, M. et al. (2015) Expression and Regulation of Cav3.2 T-Type Calcium Channels during Inflammatory Hyperalgesia in Mouse Dorsal Root Ganglion Neurons.PLoS One. 10 (5): e0127572. 29. O'Brien, D.E. et al. (2015) ERK2 Alone Drives Inflammatory Pain But Cooperates with ERK1 in Sensory Neuron Survival.J Neurosci. 35 (25): 9491-507. 31. Sheahan, T.D. et al. (2015) Voluntary Exercise Training: Analysis of Mice in Uninjured, Inflammatory, and Nerve-Injured Pain States.PLoS One. 10 (7): e0133191. 32. Park, S.I. et al. (2015) Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics.Nat Biotechnol. Nov 9. [Epub ahead of print] 33. Vogelaar CF et al. (2015) Pharmacological Suppression of CNS Scarring by Deferoxamine Reduces Lesion Volume and Increases Regeneration in an In Vitro Model for Astroglial-Fibrotic Scarring and in Rat Spinal Cord Injury In Vivo.PLoS One. 10 (7): e0134371. 34. Chetty, R. et al. (2006) Pancreatic endocrine tumour with ductules: further observations of an unusual histological subtype.Pathology. 38 (1): 5-9.
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