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Mouse Anti-Human Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P01233 |
|---|---|
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Isotype | IgG1 |
| Clone Names | P1G7F12 (BIO-BCG-005) |
| Purification | Purified IgG prepared by affinity chromatography on Protein A |
|---|---|
| Immunogen | Human Chorionic Gonadotropin beta subunit from human pregnancy urine |
| Shelf Life | 18 months from date of despatch. |
| Other Names | Choriogonadotropin subunit beta, CG-beta, Chorionic gonadotrophin chain beta, CGB, CGB3 |
| Target/Specificity | Mouse anti-hCG beta (free specific) antibody, clone P1G7F12 (BIO-BCG-005) recognizes the beta subunit of human chorionic gonadotropin (hCG).Minimal cross-reactivity (0.5%) has been observed with the intact hCG molecule and negligible reactivity has been shown with the human luteinizing hormone (LH), follicle-stimulating hormone (FSH) and thyroid-stimulating hormone (TSH). Human chorionic gonadotropin exists in 5 different variants (hCG, sulfated hCG, hyperglycosylated hCG, free beta hCG and hyperglycosylated free beta) that share the same amino acid sequence but have different functions (Cole 2012). hCG is a glycoprotein of 237 amino acids. Regular hCG has a molecular weight of ~36kDa where oligosaccharides account for 25-30% of the MW (Cole 2010). hCG is composed of a 92-amino acid alpha subunit, common to the LH, FSH and TSH hormones, and of a unique beta subunit, which is recognized by Mouse anti-hCG beta antibody, clone P1G7F12.Production of progesterone is not the only role of hCG: it also has numerous other functions, during pregnancy and as a marker for certain cancers (Cole 2012), (Cole 2010) and (Cole 2009). |
| Preservative & Stabilisers | 0.09% Sodium Azide (NaN3) |
| Storage | Store at +4℃ or at -20 ℃. |
| Precautions | Anti-hCG beta (Free Specific) Antibody, clone P1G7F12 (BIO-BCG-005) is for research use only and not for use in diagnostic or therapeutic procedures. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
1. Cole, L.A. (2009) Human chorionic gonadotropin tests.Expert Rev Mol Diagn. 9:721-472. Cole, L.A. (2010) Biological functions of hCG and hCG-related molecules.Reprod Biol Endocrinol. 8:102-115.3. Cole, L.A. (2012) hCG, the wonder of today's science.Reprod Biol Endocrinol. 10:24-41
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