|Application ||IHC-F, E|
|Clone Names||C11 (2F2/51)|
|Calculated MW||138941 Da|
|Purification||Ig fraction prepared by DEAE-cellulose chromatography and ammonium sulphate fractionation|
|Immunogen||Human collagen type I|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1|
|Target/Specificity||ABD10410 is specific for human collagen type I and reacts with both the native and heat denatured forms.Collagen is located in the extracellular matrix of connective tissues. It is part of the interacting network of proteoglycans and proteins that provides a structural framework for both soft and calcified connective tissues. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis.No cross reactivity was observed with albumin fractions of human serum or albumins of other species. Less than 5% binding was observed with collagen II in various assays.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Human Collagen I Antibody, clone C11 (2F2/51) is for research use only and not for use in diagnostic or therapeutic procedures.|
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