|Application ||WB, E|
|Calculated MW||43101 Da|
|Purification||Antisera to human creatine phosphokinase were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography on protein G.|
|Immunogen||CKMM from skeletal muscle|
|Shelf Life||18 months from date of despatch.|
|Other Names||Creatine kinase M-type, 22.214.171.124, Creatine kinase M chain, M-CK, Creatine kinase M-type, N-terminally processed, CKM, CKMM|
|Target/Specificity||Goat anti-Human creatine phosphokinase MM antibody recognizes creatine phosphokinase, also known as creatine kinase (CK), is an enzyme expressed by various tissues and cell types. CK catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP).In cells, the cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). There are three different isoenzymes: CKMM, CKBB and CKMB.Goat anti-Human Creatine Phosphokinase (MM) antibody recognizes the CKMM isoenzyme and was found to react ~50% with CKMB when tested in ELISA.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Creatine Phosphokinase (Mm) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Ponticos, M. et al. (1998) Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle. EMBO J. 17: 1688-1699.
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