Anti-Human Creatine Phosphokinase (BB) Antibody, clone BGN/2ba6
Mouse Anti-Human Monoclonal Antibody
|Calculated MW||42644 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Shelf Life||18 months from date of despatch.|
|Other Names||Creatine kinase B-type, 22.214.171.124, B-CK, Creatine kinase B chain, CKB, CKBB|
|Target/Specificity||Mouse anti-human creatine phosphokinase, clone BGN/2ba6 recognizes creatine phosphokinase. Also known as creatine kinase (CK), it is a dimer with a molecular weight of approximately 80,000 kDa. In vertebrate cells, the cytosolic CK enzymes consist of two different subunits, either B (brain type) or M (muscle type). They combine to produce three different isoenzymes: CKMM, CKBB and CKMB. CKBB is the major CK isoenzyme of the brain (Eppenbergeret al, 1967,Dawsonet al, 1967).Creatine phosphokinase is an enzyme expressed in tissues and cell types with high energy requirements and is involved in cellular energy homeostasis. CK reversibly catalyzes the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP) (Wallimannet al, 1992,2011).Mouse anti-human creatine phosphokinase is specific for the CKBB isoenzyme and does not react with the B subunit in CKMB. There is minimal reactivity with other human serum proteins.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human Creatine Phosphokinase (BB) Antibody, clone BGN/2ba6 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
1. Wallimann, T. et al. (2011) The creatine kinase system and pleiotropic effects of creatine.Amino Acids. 40(5):1271-96.2. Wallimann, T. et al. (1992) Intracellular compartmentation, structure and function of creatine kinase isoenzymes in tissues with high and fluctuating energy demands: the 'phosphocreatine circuit' for cellular energy homeostasis.Biochem J. 281: 21-40.3. Eppenberger, H.M. et al. (1967) The comparative enzymology of creatine kinases. I. Isolation and characterization from chicken and rabbit tissues.J Biol Chem. 242: 204-209.4. Dawson, D.M. et al. (1967) The comparative enzymology of creatine kinases. II. Physical and chemical properties.J Biol Chem. 242: 210-217.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.
Request Quote Here