|Application ||WB, E|
|Calculated MW||17507 Da|
|Purification||Purified Ig prepared by affinity chromatography on Protein G|
|Immunogen||Purified yeast cytosine deaminase.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Cytosine deaminase, 220.127.116.11, Cytosine aminohydrolase, FCY1|
|Target/Specificity||Sheep anti-Human cytosine deaminase antibody recognizes cytosine deaminase, also known as cytosine aminohydrolase. Dytosine deaminase is a 158 amino acid kDa enzyme involved in the conversion of cytosine to uracil. Sheep anti-Human cytosine deaminase antibody recognises the native antigen in ELISA and has been successfully used for detection of the enzyme by western blotting (Fuerer and Iggo 2004).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Yeast Cytosine Deaminase Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Fuerer, C. et al. (2004) 5-Fluorocytosine increases the toxicity of Wnt-targeting replicating adenoviruses that express cytosine deaminase as a late gene.Gene Ther. 11: 142-51 2. Hammer, K. et al. (2015) Engineered adenoviruses combine enhanced oncolysis with improved virus production by mesenchymal stromal carrier cells.Int J Cancer. 137 (4): 978-90. 3. Amon, A. et al. (2008) Methods and Composition for Diagnosing and Treating CancerUS patent application US 11/767,200 4. Pan, X. et al. (2003) Adenovirus-mediated gene transfer in the treatment of pancreatic cancer.Pancreas. 26: 274-8. 5. Conrad, C. et al.(2005)Δ24-hyCD adenovirus suppresses glioma growth in vivo by combining oncolysis and chemosensitization.Cancer Gene Ther. 12: 284-94. 6. Michnick, S.W. et al. (2010) A toolkit of protein-fragment complementation assays for studying and dissecting large-scale and dynamic protein-protein interactions in living cells.Methods Enzymol. 470: 335-68.
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