|Purification||Protein A chromatography|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||ABD10461 recognises diphtheria toxin (DT), secreted by certain strains of Corynebacterium diphtheriae. DT catalyzes the ADP-ribosylation of eukaryotic aminoacyl-transferase II (EF-2) using NAD as a substrate. This reaction forms the basis for its toxicity toward eukaryotic organisms. The toxin is secreted as a single polypeptide chain of about 63kDa, it is then processed to form A and B fragments both of which appear to be required for toxicity. ABD10461 is specific for the intact toxin/toxoid and does not react with free A or B subunits.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Diphtheria Toxin Antibody, clone 8G1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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